I suspect one of our hypervisors is faulty but at this stage I can't prove it.

We're running RHV 4.1.7 (about to upgrade to v4.1.10 in a few days).  

I'm planning on create a negative host affinity rule to prevent all current existing VMs from running on the suspect host.  Afterwards I'll create a couple of test VMs and put them in a positive host affinity rule so they only run on the suspect host.  

There are about 150 existing VMs, are there any known problems with host affinity rules and putting 150 or so VMs in the group?

This is production so I need to be careful.

Thanks