Nir,
The use cases of my current configuration is a mix of duplicated data clusters (Percona/Consul/CouchBase) and ephemeral systems (web servers) that work perfectly when 'locked' to a local host These are built in such a way that losing a physical host reduces redundancy but isn't outwardly service degrading. The other side is the duplicated databases (namely Percona) that would induce a fairly high level of NAS bandwidth that is avoided when they leverage the local storage on their host system.
The goal would be to have the ability to house the highly redundant and/or ephemeral systems to be housed on the hosts local storage, whereas guests that need HA or one-offs would be housed using the NAS allowing seamless HA or online migration.