I'm noticing this on 4.3.8 and I don't have understood exactly the raising condition, if UI based or what
At first I thought it was the bootable flag, but it is not, apparently

vm1 powered on with two disks
I select the VM then Disks subtab
select line of second disk --> edit --> OK
All goes well
Then, remaining in the same Disks subtab window  I select the line of the first disk --> Edit --> OK
And now I get the error window:
"
Error while executing action:

vm1:
"
?
Then I go and select another powered on VM, vm2, with only one disk, the one with bootable flag, and I'm able to edit it successfully.
Then I come back and select vm1 and Disks subtab, select again the first line of the boot disk --> Edit --> OK
and I'm able to edit with success..... but eg if I want to modify both alias and description fields I have to do one at a time, otherwise if in the same window I try to modify both and then press OK I still get the error message above.

Can anyone verify/test? I was able to reproduce on bot oVirt 4.3.8 and RHV 4.3.8

Gianluca